Total synthesis of (+/-)-neovibsanin B.

نویسندگان

  • Hiroshi Imagawa
  • Hayato Saijo
  • Takahiro Kurisaki
  • Hirofumi Yamamoto
  • Miwa Kubo
  • Yoshiyasu Fukuyama
  • Mugio Nishizawa
چکیده

(+/-)-Neovibsanin B was synthesized based on a DMI-accelerated intramolecular Diels-Alder reaction followed by oxy-Michael addition-lactonization. The synthetic (+/-)-neovibsanin B induced similar morphological changes in NGF-mediated PC12 cells compared with natural (+)-neovibsanin B.

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عنوان ژورنال:
  • Organic letters

دوره 11 6  شماره 

صفحات  -

تاریخ انتشار 2009